Dr. David Sinclair is a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is best known for his work on understanding why we age and how to slow its effects.
At Harvard Medical School, his laboratory’s research has focused primarily on understanding the role of sirtuins in disease and aging, with associated interests in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration and cancer.(1)
Professor Sinclair is co-founder of several biotechnology companies (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity), an inventor on 35 patents and has received more than 25 awards and honors.
TIME magazine has listed Dr. Sinclair as one of the “100 most influential people in the world”.
It seems evident that this man is knowledgeable about how we age and how to improve our healthspan, if not our lifespan. What he and his family does is take NMN. Professor Sinclair is so convinced of NMN’s safety and efficacy that not only has he been taking it himself, so has his wife, mother and 77-year-old father.
Here’s how Professor Sinclair and his family has thus far responded to taking NMN: (2)
- Before he started taking a 500mg NMN pill every morning, 47-year-old Professor Sinclair had his blood tested and was told his body had a biological age of 58. After consuming NMN for three months, he was tested again and his biological age was 32.
- When Sinclair’s mother had her left lung removed, he was told by her doctors that her remaining life expectancy was about a year. Sinclair was not accepting that and he prescribed his mother NMN and she lived for 20 years.
- Sinclair’s 77 year old father has taken NMN which has reduced his apparent age by about two or three decades and he has successfully taken up mountaineering.
- Sinclair’s younger brother was so affected by being outpaced by his 77 year old father that he too is now taking NMN.
About his father, Dr. Sinclair says:
“He’s as vigorous as he was in his 20s and 30s, and he seems to be getting more energetic.(3)
One of the most prolific researchers on NMN, Dr. Sinclair recently obtained funding for the first long-term lifespan study in mice involving supplementation with NMN. He and his fellow researchers expect that NMN will boost NAD+ metabolism enough to reduce aging markers and increase sirtuin activity. (4)
Joe Garma has written more than 670 articles on his anti-aging blog, GarmaOnHealth, and is currently writing a book, The Ageproof Method, 12 Biohacks for A Long and Strong Life. Prohealth Longevity readers can get his four-part guide, Transform Your Body and Mind here.