Life Extension

TMG (trimethylglycine), (500 mg, 60 liquid vegetarian caps) by Life Extension

SKU: N0552



Promotes Healthy Homocysteine Levels*

  • Beneficial to heart health*
  • Hastens the conversion of homocysteine back to methionine*
  • For a better value, check out our ProHealth brand TMG
Supplement Facts
Supplement Facts
Serving Size: 2 liquid vegetarian capsules
Servings Per Container: 30
Amount Per Serving %DV
Trimethylglycine (TMG) (as betaine anhydrous) 1000 mg *
* Daily Value not established
  • Suggested Use: Take two (2) capsules in the morning with or without food, or as recommended by a healthcare practitioner. TMG should be taken with co-factors B6, B12, and folic acid.
  • Storage: KEEP OUT OF REACH OF CHILDREN. Store tightly closed in a cool, dry place.
  • Contraindications: If muscle tension or headaches occur, reduce dose or discontinue product, and inform your physician if they do not subside. Do not exceed recommended dose. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
  • Other Ingredients: Glycerin, vegetable cellulose (capsule), purified water.

Trimethylglycine (TMG) is also called glycine betaine, but the name trimethylglycine signifies that it has three methyl groups attached to each molecule of glycine. TMG was discovered to be beneficial to heart health back in the 1950s.

TMG operates along a pathway similar to that of vitamin B12: It is a "methyl donor," providing extra methyl groups to hasten the conversion of homocysteine (a know risk factor in heart disease) back to methionine.

When a TMG methyl group is donated to a molecule of homocysteine, it converts to the non-toxic amino acid, methionine. Research showing TMG's ability to promote healthy levels of homocysteine, alone or in conjunction with other nutrients, confirms its status as an important nutrient for cardiovascular health.

For example, in a recent cross-sectional survey study, participants who consumed > 360 mg/d of TMG had, on average, 10% lower concentrations of homocysteine and 19% lower concentrations of C-reactive protein than those who consumed < 260 mg/d. TMG should be taken with co-factors vitamins B6, B12, and folic acid.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

TMG (trimethylglycine), (500 mg, 60 liquid vegetarian caps) by Life Extension has a rating of 4.6 stars based on 11 reviews.