Berberine is a plant-based compound found in several different plants, including barberry and goldenseal. Berberine's health-promoting benefits come primarily from its chemical structure as an alkaloid, which increases its antioxidant, and anti-inflammatory properties.
Berberine promotes longevity by activating the AMPK pathway which senses each cell's energy status and triggers responses that help to maintain the cell's energy at its optimum level. By stimulating mitochondrial biogenesis, berberine activates genes similar to those typically turned on by exercise.
Perhaps best known for it's blood sugar stabilizing properties, both animal and human studies have demonstrated berberine's ability to support glucose metabolism and help maintain healthy blood sugar levels in those who are already in the normal range.
Additional health benefits of berberine include:
- Immune system support
- Promoting cardiovascular health
- Supporting healthy liver function
- Brain health support
- Aiding in weight loss
A Power-Packed Trio: Berberine, NMN and Trans-Resveratrol
The longevity and health benefits of berberine can become even more powerful when combined with NMN and trans-resveratrol. Both NMN and trans-resveratrol activate the expression of sirtuins – genes that regulate cellular homeostasis and repair DNA – while both berberine and trans-resveratrol activate the AMPK pathway. Together this powerful trio offers a wealth of longevity and overall health benefits.