Fat cells (adipocytes) secrete a hormone called leptin that tells our brain we have eaten enough.(5) Leptin can also facilitate the breakdown of stored triglycerides in our adipocytes via the process of lipolysis. Heavy individuals have startlinglyhigh blood levels of leptin, indicating that their cells have become resistant to the leptin that is supposed to prevent them from putting on so many fat pounds.
An extract from an African mango called Irvingia gabonensis has been shown to help support leptin sensitivity in overweight people. In a recently published study, irvingiademonstrated beneficial effects upon leptin blood levels, followed by weight loss and inches off the waistline.(1,3)