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Nootropics Depot

7,8-Dihydroxyflavone (25 mg, 60 Capsules) by Nootropics Depot

SKU: N1521

$29.99

Description

A Natural Flavone Found to Exert Cognitive Benefits*

  • Has demonstrated a protective effect against apoptosis*
  • A very promising natural compound for cognitive function*
  • Helps to restore communication between neurons*

7,8 DHF Capsules | What is 7,8 Dihydroxyflavone?

7,8-Dihydroxyflavone, also known as 7,8-DHF, is a natural flavone found in a number of species that can reach the brain and exert cognitive effects. It binds to the TrkB receptors in a similar way to BDNF, or brain derived neurotrophic factor. When the TrkB receptor is activated, neuroprotective and neurogenetive effects occur in neurons, which tend to affect the dendrites.

Dendrites are what reach out from the neurons into the synapse to participate in signaling with other neurons. 7,8-DHF has been shown to promote the growth of these dendrites, and to help restore communication between neurons in animal models. Other natural extracts, like polygala tenuifolia and bacopa monnieri  work in a similar fashion, but rather than binding directly to the TrkB receptor, they cause a release in BDNF, which then binds to the receptor.

7,8-DHF has also demonstrated a protective effect against apoptosis. 7,8-DHF can cross the blood brain barrier, and act directly on brain TrkB receptors; which is something that peripheral administration of BDNF cannot do. As such, it is a very promising natural compound for cognitive function.

7,8 DHF Dosage

As a dietary supplement, take one to two 25mg capsules of 7,8 Dihydroxyflavone daily. It appears to be subject to extensive first-pass metabolism in the liver. Due to improved bioavailability, sublingual administration (under the tongue) may be preferred.

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Supplement Facts
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
7,8-Dihydroxyflavone 25 mg *
*Daily Value not established
**Based on a 2,000 calorie diet
  • Suggested Use: As a dietary supplement, take one to two 25mg capsules of 7,8 Dihydroxyflavone daily. It appears to be subject to extensive first-pass metabolism in the liver. Due to improved bioavailability, sublingual administration (under the tongue) may be ideal.

  • Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.

  • Contraindications: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.

  • Other Ingredients: Magnesium stearate (flow agent), silicon dioxide (flow agent), vegetable cellulose (capsules).