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Age-Related Changes to Gut Metabolites Linked to Amyloid-Beta Plaques

November 24, 2020

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November 24, 2020

Age-related changes in metabolite production in the gut correlate with the presence of beta-amyloid plaques in the brain, a hallmark of Alzheimer's disease. Read more

11/24/2020

Artificial Intelligence Eye Exam Could Diagnose Parkinson's Disease Earlier

November 23, 2020

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November 23, 2020

An eye exam using artificial intelligence could detect Parkinson's disease (PD) earlier. This method using machine learning to classify PD based on changes in the retina vasculature of the eye. Read more

11/23/2020

Hyperbaric Oxygen Treatment Increases Immune Cell Telomere Length

November 23, 2020

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November 23, 2020

Hyperbaric oxygen treatments (HBOT) in healthy aging adults increased telomere length of T-cells. HBOT lengthened telomeres by 38% and decreased the presence of senescent cells by 37%. Read more

11/23/2020

Overactive Astrocyte Cells Explain Unpredictability of Alzheimer's Disease

November 19, 2020

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November 19, 2020

Researchers discovered differences between mildly and severely reactive astrocytes, which may explain why some people with Alzheimer's disease (AD) don't respond after amyloid plaques are removed. Read more

11/19/2020

Just 12 Minutes of Cardio Exercise Benefits Metabolic Health

November 18, 2020

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November 18, 2020

Twelve minutes of cardio impacts 80% of circulating metabolites, improving cardiometabolic health. Brief bouts of exercise benefit insulin resistance, oxidative stress, inflammation, and longevity pathways. Read more

11/18/2020

Feeling Stressed? Eating a Mediterranean Diet May Help

November 17, 2020

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November 17, 2020

In this study, middle-aged animals eating Mediterranean diets experienced better resilience to stress, lower cortisol, and slower nervous system aging than animals consuming a typical Western diet. Read more

11/17/2020

Chronic Inflammation and CD38 Activation Drive NAD+ Decline

November 16, 2020

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November 16, 2020

Researchers identify chronic inflammation, senescent cells, and activation of the protein CD38 as a driver of NAD+ decline, the crucial coenzyme needed for healthy metabolism, aging, and DNA repair. Read more

11/16/2020

New Potential Treatment to Manage or Delay Osteoarthritis

November 13, 2020

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November 13, 2020

The HDAC6 inhibitor Tubastatin A is a promising target to delay or treat osteoarthritis, reversing damage caused by HDAC6 overexpression, protecting the extracellular matrix and chondrocytes. Read more

11/13/2020

Weekly Physical Activity Helps Prevent Mild Cognitive Impairment Progress to Dementia

November 12, 2020

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November 12, 2020

People with mild cognitive impairment who exercised for at least ten minutes more than once per week had an 18% lower risk of developing Alzheimer's disease compared to non-exercisers. Read more

11/12/2020

APOE2 Gene Variant Correlates With Increased Longevity

November 11, 2020

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November 11, 2020

The APOE4 gene variant is associated with an increased risk of Alzheimer's disease (AD); APOE2 is protective against AD. The APOE2 variant is linked to increased lifespan, irrespective of AD. Read more

11/11/2020

Extra Virgin Olive Oil Improves Mild Cognitive Impairment, New Study Finds

November 10, 2020

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November 10, 2020

In this study, Greek adults with amnestic mild cognitive impairment who consumed high-phenolic or moderate-phenolic extra-virgin olive oil for 12 months had significantly improved cognitive scores. Read more

11/10/2020

Do People Who Eat Chili Peppers Live Longer?

November 09, 2020

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November 09, 2020

People who consume chili peppers may live longer and have a reduced risk of disease, correlational study finds. The compound capsaicin found in chilis exhibits anti-inflammatory and antioxidant effects. Read more

11/09/2020

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