NMN supplementation boosts the NAD+ pool in the intestine and activates the signaling pathways related to antioxidant, anti-inflammatory, and barrier functions that support healthy intestinal aging.
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In a recent study, Buck Institute researchers demonstrate for the first time a direct link between dietary restriction, circadian rhythm, eye health, and lifespan in fruit flies.
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Exercise triggers the release of tiny sacs (extracellular vesicles) containing an enzyme critical to synthesizing NAD+, promoting cellular crosstalk to improve health during aging.
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The compound crocin—found in saffron—benefits learning, memory, and social interaction in stressed mice by regulating an enzyme that produces NMN, a precursor to the vital molecule NAD+.
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NAD+ levels can be maintained or elevated by supplementing with a precursor to NAD+, like NMN. But which form of NMN is best — liposomal, powder, sublingual, or capsules?
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ProHealth Longevity reviews the categories of natural products with properties that slow aging and promote healthy lifespan extension, and the mechanisms of targets for anti-aging evaluation.
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The correction of NAD+ depletion in mouse nerve cells supports axonal health — the projections of neurons — in the face of blood sugar dysregulation or other stressors.
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Found in broccoli, sulforaphane is a powerful antioxidant compound that supports cardiometabolic and cognitive health by fighting inflammation — but its bioavailability on its own is low.
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Supplementing with 300 mg of NMN per day for 60 days increases blood serum NAD+ levels, improves quality of life and physical endurance, and reduces insulin resistance.
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Researchers identify seven hours as the optimal sleep duration; both insufficient and excessive sleep duration were significantly associated with a decline in cognition with age.
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A compound of ginger called gingerenone A produces potent senescence-clearing effects, representing a promising natural compound for fighting this aspect of cellular aging.
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